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4&rsquo-hydroxy Atomoxetine Glucuronide(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4&rsquo-hydroxy Atomoxetine Glucuronide(hydrate)图片
包装:1mg
市场价:10886元

产品介绍
A metabolite of atomoxetine
Canonical SMILESOC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC(C)=C(C=C2)O[C@@H](C3=CC=CC=C3)CCNC)=O.O
分子式C23H29NO8·XH2O
分子量447.5
溶解度Methanol: slightly, sonicated,Water: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4’-hydroxy Atomoxetine glucuronide is a metabolite of the norepinephrine transporter (NET) inhibitor atomoxetine .1It is formed from atomoxetine by glucuronidation of the intermediate metabolite 4-hydroxy atomoxetine.2

1.Todor, I., Popa, A., Neag, M., et al.Evaluation of a potential metabolism-mediated drug-drug interaction between atomoxetine and bupropion in healthy volunteersJ. Pharm. Pharm. Sci.19(2)198-207(2016) 2.Sauer, J.-M., Ring, B.J., and Witcher, J.W.Clinical pharmacokinetics of atomoxetineClin. Pharmacokinet.44(6)571-590(2005)