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7-Ethoxy-4-(trifluoromethyl)coumarin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
7-Ethoxy-4-(trifluoromethyl)coumarin图片
CAS NO:115453-82-2
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
7-Ethoxy-4-(trifluoromethyl)coumarin 是细胞色素 P450 超家族各种酶的荧光底物
Cas No.115453-82-2
别名7-乙氧基-4-(三氟甲基)香豆素
Canonical SMILESO=C1OC2=C(C(C(F)(F)F)=C1)C=CC(OCC)=C2
分子式C12H9F3O3
分子量258.2
溶解度Chloroform: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-Ethoxy-5-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon O-deethylation by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.

1.Buters, J.T.M., Schiller, C.D., and Chou, R.C.A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man. Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarinBiochem. Pharmacol.46(9)1577-1584(1993)