| CAS NO: | 910297-52-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 910297-52-8 |
| 别名 | 达沙替尼N氧化物；达沙替尼杂质 |
| Canonical SMILES | OCCN(CCN1C2=CC(NC3=NC=C(C(NC4=C(Cl)C=CC=C4C)=O)S3)=NC(C)=N2)(CC1)=O |
| 分子式 | C22H26ClN7O3S |
| 分子量 | 504 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib .1 It is also a potential impurity in commercial preparations of dasatinib.2 |1. Christopher, L.J., Cui, D., Li, W., et al. Biotransformation of [14C]dasatinib: In vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab. Dispos. 36(7), 1341-1356 (2008).|2. PlachkÁ, K., •vec, F., and NovÁkovÁ, L. Ultra-high performance supercritical fluid chromatography in impurity control: Searching for generic screening approach. Anal. Chim. Acta 1039, 149-161 (2018). |
m.cnreagent.com