| 包装 | 价格(元) |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Canonical SMILES | OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1.[Na].O |
| 分子式 | C10H14N5O7P·XNa [XH2O] |
| 分子量 | 347.2 |
| 溶解度 | PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine . 1.Rao, F., Yaning, Q., Murugan, E., et al.20,30-cAMP hydrolysis bymetal-dependent phosphodiesterases containing DHH, EAL, and HD domains is non-specific: Implications for PDE screeningBiochem. Bioph. Res. Commun.398(3)500-505(2010) 2.Jackson, E.K., Gillespie, D.G., and Dubey, R.K.2’-AMP and 3’-AMP inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptorsJ. Pharmacol. Exp. Ther.337(2)444-450(2011) |
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