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bio-THZ1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
bio-THZ1图片
CAS NO:1604811-14-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
bio-THZ1 是THZ1 的生物素结构,与CDK7 不可逆的结合。THZ1 是有效,选择性的共价 CDK7 抑制剂,IC50 为 3.2 nM。
Cas No.1604811-14-4
分子式C52H65ClN12O8S
分子量1053.67
溶解度DMSO : 120 mg/mL (113.89 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM[1].

[1]. Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul 31;511(7511):616-20.