CAS NO: | 779353-02-5 |
包装: | 5mg |
市场价: | 900元 |
Cas No. | 779353-02-5 |
别名 | (S)-2-(1-(3-乙基-7-((吡啶-3-基甲基)氨基)吡唑并[1,5-A]嘧啶-5-基) |
分子式 | C21H28N6O |
分子量 | 380.49 |
溶解度 | DMSO : 50 mg/mL (131.41 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1]. Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1]. [1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1. |