您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > CDK-IN-6
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CDK-IN-6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CDK-IN-6图片
CAS NO:779353-02-5
包装:5mg
市场价:900元

产品介绍
CDK-IN-6,是一类吡唑并[1,5-a]嘧啶化合物,是一种具有抗癌活性的 CDK 抑制剂。
Cas No.779353-02-5
别名(S)-2-(1-(3-乙基-7-((吡啶-3-基甲基)氨基)吡唑并[1,5-A]嘧啶-5-基)
分子式C21H28N6O
分子量380.49
溶解度DMSO : 50 mg/mL (131.41 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CDK-IN-6, a class of pyrazolo[1,5-a]pyrimidine compound, is a CDK inhibitor with anticancer activities[1].

Individual CDK’s, such as, CDK1, CDK2, CDK3, CDK4, CDK5, CDK6 and CDK7, CDK8 and the like, perform distinct roles in cell cycle progression and can be classified as either G1, S, or G2M phase enzymes. Uncontrolled proliferation is a hallmark of cancer cells, and misregulation of CDK function occurs with high frequency in many important solid tumors[1].

[1]. Timothy Guzi, et al. Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. US20040209878A1.