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Quinizarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Quinizarin图片
CAS NO:81-64-1
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1g电议

产品介绍

Quinizarin(1,4-Dihydroxyanthraquinone)是Doxorubicin、Daunorubicin、Adriamycin等抗癌药物的一部分,通过插入方式与DNA相互作用(Kd=86.1μM)。Quinizarin是一种杀菌剂和杀虫剂,并已显示出抑制肿瘤细胞生长的能力。

Cas No.81-64-1
别名1,4-二羟基蒽醌; 1,4-Dihydroxyanthraquinone
Canonical SMILESO=C1C2=C(C=CC=C2)C(C3=C(O)C=CC(O)=C13)=O
分子式C14H8O4
分子量240.21
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (Kd=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth[1][2].

1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution[1].

[1]. VerebovA V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55. [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin. [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373.