Cas No. | 626604-39-5 |
别名 | GSK-3BETA抑制剂XI |
化学名 | 3-[1-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-(2-pyrazinyl)-1H-pyrrole-2,5-dione |
Canonical SMILES | O=C(N1)C(C2=CN=CC=N2)=C(C3=CN(CCCO)C4=C3C=CC=N4)C1=O |
分子式 | C18H15N5O3 |
分子量 | 349.3 |
溶解度 | DMSO: 5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | GSK3β inhibitor XI is a potent inhibitor of glycogen synthase kinase 3β (GSK3β; Ki = 25 nM). It is selective for GSK3β over a panel of 79 kinases at a concentration of 10 μM. GSK3β inhibitor XI inhibits GSK3β in HEK293 cells (EC50 = 32 nM). |