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O,O-Dimethyl-cannabigerol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
O,O-Dimethyl-cannabigerol图片
CAS NO:29106-16-9
包装与价格：
包装价格(元)
5mg电议
10mg电议

产品介绍
O,O-Dimethyl-cannabigerol 是一种可从大麻中提取的天然物质。O,O-Dimethyl-cannabigerol 对金黄色葡萄球菌耐药菌株具有抗菌作用 (MIC 范围为 1-2 μg/mL)。O,O-Dimethyl-cannabigerol 属于非精神活性物质。
Cas No.29106-16-9
别名受控
分子式C23H36O2
分子量344.53
溶解度DMSO : 55 mg/mL (159.64 mM; Need ultrasonic)|Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

O,O-Dimethyl-cannabigerol is a natural product from Cannabis sativa. O,O-Dimethyl-cannabigerol has an antibacterial effect on drug-resistant strains of Staphylococcus aureus (MIC ranging from 1 to 2 µg/mL)[1]. O,O-Dimethyl-cannabigerol is a nonpsychoactive constituent[2][3].

O,O-Dimethyl-cannabigerol (compound 1) inhibits KB cells growth with IC50s of 44.55 μM (MTT assay) and 69.4 μM (SRB assay)[2].O,O-Dimethyl-cannabigerol (0-100 μM; 48 hours) induces cell cytotoxic in NIH 3T3 fibroblasts, with CD50s of 60.46 μM (MTT assay) and 82.98 μM (SRB assay)[2].O,O-Dimethyl-cannabigerol shows antitumor efficacy against melanoma cells of a mouse’s skin with an IC50 of 31.3 μM[2].

[1]. Appendino G, et al. Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. J Nat Prod. 2008;71(8):1427-1430.
[2]. Han DS, et al. Synthesis and cytotoxic effects of deoxy-tomentellin. Arch Pharm Res. 2000;23(2):121-127.
[3]. Caprioglio D, et al. O-Methyl Phytocannabinoids: Semi-synthesis, Analysis in Cannabis Flowerheads, and Biological Activity. Planta Med. 2019;85(11-12):981-986.