您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > ARX-1796
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
ARX-1796
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ARX-1796图片
CAS NO:2245880-46-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
ARX-1796 (AV-006) 是一种 Avibactam 前药,是口服生物利用的 β-内酰胺酶 (β-lactamase) 抑制剂。Avibactam 具有对 A 类和 C 类β-内酰胺酶的抑制谱,包括 ESBLs、AmpC 和肺炎克雷伯菌碳青霉烯酶 (KPC) 酶。
Cas No.2245880-46-8
别名AV-006
分子式C14H23N3O8S
分子量393.41
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ARX-1796 (AV-006), an Avibactam prodrug, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes[1][2].

[1]. Veeraraghavan B, et al. Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections. Infect Dis Ther. 2021;10(4):1815-1835. [2]. Falcone M, et al. Spotlight on ceftazidime/avibactam: a new option for MDR Gram-negative infections. J Antimicrob Chemother. 2016;71(10):2713-2722.