| CAS NO: | 28115-68-6 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 28115-68-6 |
| 别名 | (-)-Pluviatolide |
| Canonical SMILES | O=C(OC1)[C@H](CC2=CC=C(O)C(OC)=C2)[C@H]1CC3=CC=C4C(OCO4)=C3 |
| 分子式 | C20H20O6 |
| 分子量 | 356.4 |
| 溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties.1,2,3 It scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl radicals in cell-free assays (IC50s = 23.2 and 88.5 μM, respectively).1 Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 μM.2 It decreases contractions induced by acetylcholine in isolated guinea pig ileum when used at concentrations of 30 and 100 μM.3 |1. Li, D.-Q., Wang, D., Zhou, L., et al. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense. J. Asian Nat. Prod. Res. 19(5), 519-527 (2017).|2. Muta, Y., Oyama, S., Umezawa, T., et al. Inhibitory effects of lignans on the activity of human matrix metalloproteinase 7 (matrilysin). J. Agric. Food Chem. 52(19), 5888-5894 (2004).|3. Zhang, G., Shimokawa, S., Mochizuki, M., et al. Chemical constituents of Aristolochia constricta: Antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. J. Nat. Prod. 71(7), 1167-1172 (2008). |
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