CAS NO: | 1504588-00-4 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 1504588-00-4 |
Canonical SMILES | ClC1=C(CNC(C2=CC=C(N(C3=C(C)C=CC(C)=C3)C=N4)C4=C2)=O)C=CC=C1 |
分子式 | C23H20ClN3O |
分子量 | 389.9 |
溶解度 | DMSO: 5 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NAB 2 is an inhibitor of α-synuclein-induced toxicity. It prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells. NAB 2 also prevents formation of α-synuclein foci in wild-type yeast cells, an effect that is prevented by the rsp5G747E point mutation. |