PIM-1 Inhibitor 2 是一种有效的 ATP 竞争性 Pim-1 抑制剂，Ki 为 91 nM。 PIM-1 Inhibitor 2 靶向 ATP 结合激酶铰链区，而不是通过形成经典的氢键。
| Cas No. | 477845-12-8 |
| 化学名 | 4-[3-(4-chlorophenyl)-2,1-benzoxazol-5-yl]pyrimidin-2-amine |
| Canonical SMILES | C1=CC(=CC=C1C2=C3C=C(C=CC3=NO2)C4=NC(=NC=C4)N)Cl |
| 分子式 | C17H11CIN4O |
| 分子量 | 322.75 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | Store at 4℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Potent Pim-1 kinase inhibitor (Ki= 91 nM). |
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