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SORT-PGRN interaction inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SORT-PGRN interaction inhibitor 1图片
CAS NO:100957-85-5
包装与价格:
包装价格(元)
100mg电议
250mg电议

产品介绍
SORT-PGRNinteractioninhibitor1是一种有效的sortilin-progranulin相互作用的抑制剂,IC50为2μM。
Cas No.100957-85-5
别名1-苄基-3-叔丁基-1H-吡唑-5-羧酸
Canonical SMILESO=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O
分子式C15H18N2O2
分子量258.32
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].

SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin[1].

[1]. Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.