CAS NO: | 100957-85-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
Cas No. | 100957-85-5 |
别名 | 1-苄基-3-叔丁基-1H-吡唑-5-羧酸 |
Canonical SMILES | O=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O |
分子式 | C15H18N2O2 |
分子量 | 258.32 |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1]. SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin[1]. [1]. Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403. |