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DEL-22379
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DEL-22379图片
CAS NO:181223-80-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
DEL22379, DEL 22379
产品介绍

生物活性

DEL-22379是一种有效的选择性ERK二聚体抑制剂,可抑制ERK二聚体而不影响ERK磷酸化,阻止由RAS-ERK途径癌基因驱动的肿瘤发生。

靶点信息

ERK
0.5 μM

化学数据

目录号A15802
作用机制Inhibitor (抑制剂)
M. Wt444.55
FormulaC26H28N4O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.181223-80-3
SynonymsDEL22379, DEL 22379
SMILESO=C1NC2=CC=C(NC(CCN3CCCCC3)=O)C=C2C1=CC4=CNC5=CC=C(OC)C=C54

溶解度

In vitroDMSO79 mg/mL (177.71 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.49 mL112.47 mL224.95 mL
0.5 mM4.5 mL22.49 mL44.99 mL
1 mM2.25 mL11.25 mL22.49 mL
5 mM0.45 mL2.25 mL4.5 mL

*The above data is based on the productmolecular weight 444.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.