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PF 04479745
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF 04479745图片
CAS NO:1065110-43-1
包装:1mg
市场价:1544元

产品介绍
PF 04479745 是一种有效的选择性 5-HT2C 受体激动剂(EC50:10 nM,ki:15 nM)。 PF 04479745 可用于高血压等心血管疾病的研究。
Cas No.1065110-43-1
Canonical SMILESC[C@@H]1C2=NC(CC3=CC=CC=C3)=NC(NC)=C2CCNC1
分子式C17H22N4
分子量282.39
溶解度DMSO|28.24|100|ethanol|28.24|100|
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Potent and selective 5-HT2C agonist (EC50 = 10 nM). Exhibits > 100-fold selectivity over a panel of 90 receptors, enzymes and ion channels, except for 5-HT2A (IC50 = 360 nM antagonist), 5-HT2B (EC50 = 67 nM antagonist), 5-HT1A and 5-HT6 (functional activity not tested).