包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Canonical SMILES | ClC1=C(C=CC=C2)C2=C(OCCC3=C[N+]([O-])=CC=C3)C=C1 |
分子式 | C17H14ClNO2 |
分子量 | 299.75 |
溶解度 | DMSO|29.98|100|ethanol|29.98|100| |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Potent and selective GPR84 biased agonist (EC50 = 33 nM). Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis. |