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Endomorphin 2 TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Endomorphin 2 TFA图片
CAS NO:1276124-00-5
包装与价格:
包装价格(元)
5mg电议
10mM (in 1mL Water)电议
25mg电议
50mg电议
100mg电议

产品介绍
Endomorphin 2 TFA,一种高度选择性的高亲和力 μ-opioid 受体激动剂,对 kappa3 结合位点具有高亲和力 ,Ki 为 20 到 30 nM 之间。
Cas No.1276124-00-5
别名内吗啡肽 2 三氟乙酸盐
Canonical SMILESO=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](CC4=CC=C(C=C4)O)N)=O)CCC3)=O)=O.OC(C(F)(F)F)=O
分子式C34H38F3N5O7
分子量685.69
溶解度Water: 62.5 mg/mL (91.15 mM); DMSO:< 1 mg/mL (insoluble or slightly soluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Endomorphin 2 TFA, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM[1]. Ki: 20-30 nM (kappa3 opioid receptor)[1]

[1]. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.