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Tazarotenic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tazarotenic Acid图片
CAS NO:118292-41-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
他扎罗汀酸是他扎罗汀的代谢产物。
Cas No.118292-41-4
别名他扎罗汀酸,AGN 190299
Canonical SMILESOC(C1=CC=C(C#CC2=CC(C(C)(C)CCS3)=C3C=C2)N=C1)=O
分子式C19H17NO2S
分子量323.4
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tazarotenic acid is an active metabolite of tazarotene, an acetylenic retinoid prodrug that induces epidermal hyperplasia with an ED50 value of 100 nM. Tazarotenic acid selectively binds retinoic acid receptors (RAR-β and RAR-γ) in vitro. It has a relatively short elimination half-life of one to two hours and is metabolized by cytochrome P450 (CYP) isoforms CYP2C8, CYP26A1, and CYP26B1.