| CAS NO: | 1560894-05-4 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 1560894-05-4 |
| Canonical SMILES | CC1=C(CCN2C(C3=CC=C(C(OC)=O)C=C3)C(C(C)=O)=C(O)C2=O)C4=CC=CC=C4N1 |
| 分子式 | C25H24N2O5 |
| 分子量 | 432.5 |
| 溶解度 | DMSO: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PYD-106 is a positive allosteric modulator of NR2C subunit-containing NMDA receptors (NMDARs).1It enhances glutamate-induced maximal current responses in HEK293 cells expressing NR1/NR2C NMDA receptors (EC50= 13 µM). PYD-106 is selective for NR2C subunit-containing NMDA receptors over NRA-, NR2B-, and NR2D-subunit containing NMDA receptors inXenopusoocytes expressing NR1/NR2 heteromeric NMDA receptors at 30 µM. 1.Khatri, A., Burger, P.B., Swanger, S.A., et al.Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulatorMol. Pharmacol.86(5)548-560(2014) |
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