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MNI-caged-L-glutamate(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MNI-caged-L-glutamate(trifluoroacetate salt)图片
CAS NO:2226362-29-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A caged neurotransmitter used with photolysis
Cas No.2226362-29-2
Canonical SMILESCOC1=C2C(N(C(CC[C@H](N)C(O)=O)=O)CC2)=C([N+]([O-])=O)C=C1.FC(F)(C(O)=O)F
分子式C14H17N3O6.CF3COOH
分子量437.3
溶解度Ethanol: 0.25 mg/mL,PBS (pH 7.2): 5 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations).1Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds.1This compound can be used to investigate the mechanisms of fast synaptic glutamate receptorsin situ.

1.Canepari, M., Nelson, L., Papageorgiou, G., et al.Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmittersJ.Neurosci.Methods112(1)29-42(2001)