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Heptaminol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Heptaminol图片
CAS NO:372-66-7
包装:500mg
市场价:1210元

产品介绍
An aliphatic amine with cardiotonic and sympathomimetic activities
Cas No.372-66-7
别名6-氨基-2-甲基-2-庚醇
Canonical SMILESCC(N)CCCC(C)(O)C
分子式C8H19NO
分子量145.2
溶解度DMF: 15mg/mL,DMSO: 10mg/mL,Ethanol: 15mg/mL,PBS (pH 7.2): 10mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Heptaminol is an aliphatic amine with cardiotonic and sympathomimetic activities.1,2,3It decreases the amplitude of peak calcium currents by 30% in isolated guinea pig ventricular myocytes when used at a concentration of 100 µM.1Heptaminol inhibits norepinephrine uptake and induces catecholamine release in primary bovine chromaffin cells.3,2It increases blood pressure in cats when administered intravenously at a dose of 15 mg, an effect that can be blocked by reserpine .4

1.Peineau, N., Mongo, K.G., Le Guennec, J.-Y., et al.Alteration of the L-type calcium current in guinea-pig single ventricular myocytes by heptaminol hydrochlorideBr. J. Pharmacol.107(1)104-108(1992) 2.Grobecker, H.On the mode of action of heptaminolNaunyn Schmiedebergs Arch Pharmakol.266(4)339-340(1970) 3.Delicado, E.G., Fideu, M.D., Miras-Portugal, M.T., et al.Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cellsBiochem. Pharmacol.40(4)821-825(1990) 4.Garrett, J., Osswald, W., and Goncalves Moriera, M.Mechanism of cardiovascular actions of heptanolaminesBr. J. Pharmacol. Chemother.18(1)49-60(1962)