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Cyfluthrin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cyfluthrin图片
CAS NO:68359-37-5
包装:100mg
市场价:438元

产品介绍
Cyfluthrin 是一种 II 型拟除虫菊酯,对多种昆虫都有作用。
Cas No.68359-37-5
别名氟氯氰菊酯,beta-Cyfluthrin
Canonical SMILESO=C(C1C(C)(C)C1/C=C(Cl)\Cl)OC(C#N)C2=CC(OC3=CC=CC=C3)=C(F)C=C2
分子式C22H18Cl2FNO3
分子量434.3
溶解度Chloroform: Slightly Soluble,Methanol: Heated
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cyfluthrin is a pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1,2It slowly activates rat recombinant Nav1.8 channels, delays inactivation by longer than 40 ms, and induces persistent tail currents in channels expressed inX. laevisoocytes.1It also decreases the mean burst rate in rat primary neurons (IC50= 0.99 μM, respectively).2Cyfluthrin is toxic to various insects, includingA. melinus,G. ashmeadi,E. eremicus, andE. formosa(LC50s = 7, 67, 96, and 63 ng/ml, respectively) and theA. sinensismosquito (LC50= 0.446 ppm).3,4It is also toxic toA. melliferahoneybees (LD50= 0.22 ppm), affecting locomotor activity and wing fanning behavior with an increase in the mean bout duration of time spent upside down, indicating disruption of the righting reflex, and a decrease in wing fanning behavior when administered at a dose of 10 ng/bee.5Formulations containing cyfluthrin have been used for the control of insects in agriculture and for non-commercial purposes.

1.Choi, J.S., and Soderlund, D.M.Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Nav1.8 sodium channels expressed in Xenopus oocytesToxicol. Appl. Pharmacol.211(3)233-244(2006) 2.Baskar, M.K., and Murthy, P.B.In vitro evaluation of pyrethroid-mediated changes on neuronal burst parameters using microelectrode arraysNeuroToxicology57270-281(2016) 3.Prabhaker, N., Morse, J.G., Castle, S.J., et al.Toxicity of seven foliar insecticides to four insect parasitoids attacking citrus and cotton pestsJ. Econ. Entomol.100(4)1053-1061(2007) 4.Chang, K.-S., Yoo, D.-H., Shin, E.-H., et al.Susceptibility and resistance of field populations of Anopheles sinensis (Diptera: Culicidae) collected from Paju to 13 insecticidesOsong Public Health Res. Perspect.4(2)76-80(2013) 5.Oliver, C.J., Softley, S., Williamson, S.M., et al.Pyrethroids and nectar toxins have subtle effects on the motor function, grooming and wing fanning behaviour of honeybees (Apis mellifera)PLoS One10(8):e0133733(2015)