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ATPA(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ATPA(hydrate)图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
An agonist of GluR5
Canonical SMILESNC(C(O)=O)CC1=C(C(C)(C)C)ONC1=O.O
分子式C10H16N2O4.XH2O
分子量228.2
溶解度Water: 10 mM
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ATPA is an agonist of ionotropic glutamate receptor 5 (GluR5/GluK1; Ki= 0.0043 µM).1It is selective for GluR5 over GluR1-4 (Kis = 6-14 µM), as well as GluR6 (Ki= >1,000 µM). ATPA induces inward currents in HEK293 cells expressing recombinant human GluR5 and isolated rat dorsal root ganglion (DRG) neurons (EC50s = 2.1 and 0.6 µM, respectively).

1.Clarke, V.R., Ballyk, B.A., Hoo, K.H., et al.A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmissionNature389(6651)599-603(1997)