您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Picrotoxinin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Picrotoxinin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Picrotoxinin图片
CAS NO:17617-45-7
包装:10mg
市场价:3330元

产品介绍
Picrotoxinin是一种有效的惊厥药,是一种氯通道(chloridechannel) 阻断剂。Picrotoxinin是一种非竞争性的GABAA受体拮抗剂,负向调节GABA对GABAA受体的作用。
Cas No.17617-45-7
别名木防己苦毒宁
Canonical SMILESO=C1[C@]([C@@H]2C(C)=C)([H])[C@]3(O)C[C@]4([H])[C@](O4)(C(O5)=O)[C@]3(C)[C@@]5([H])[C@]2([H])O1
分子式C15H16O6
分子量292.28
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors[1].

[1]. Ng CC, et al. Effects of bilobalide, ginkgolide B and picrotoxinin on GABAA receptor modulation by structurally diverse positive modulators. Eur J Pharmacol. 2017 Jul 5;806:83-90.