| CAS NO: | 2158198-77-5 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 2158198-77-5 | ||||||||
| 分子式 | C17H11BrCl2N2O3 | ||||||||
| 分子量 | 442.09 | ||||||||
| 溶解度 | DMSO : 50 mg/mL (113.10 mM; ultrasonic and warming and heat to 60°C) | ||||||||
| 储存条件 | Store at -20°C | ||||||||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||||||||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request | ||||||||
| 产品描述 | Chst15-IN-1 is a potent reversible covalentChst15inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely relatedglycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selectivesulfotransferaseinhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair[1]. Chst15-IN-1 (25 μM; 24 hours; Neu7 astrocytes) is selective for sulfotransferases over the myriad of reactive cysteine-containing proteins. Chst15-IN-1 (10 and 25 μM; Neu7 astrocytes) shows a significant dose dependent decrease in cell-surface CS-E expression[1]. Chst15-IN-1 (3.0 mg/kg; i.v.) has a moderate clearance of 21 mL/min/kg, moderate volume of distribution of 0.97 L/kg, and short terminal half-life of 1.6 hours[1].
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