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7-Methylguanosine 5&rsquo-diphosphate sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Methylguanosine 5&rsquo-diphosphate sodium图片
CAS NO:104809-16-7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium,一种 cap 类似物,可以用来合成 mRNA cap 类似物。
Cas No.104809-16-7
别名7-Methyl-GDP sodium; m7GDP sodium
分子式C11H16N5NaO11P2
分子量479.21
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].

7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].

[1]. Sonenberg N, et al. Nonspecific effect of m7GMP on protein-RNA interactions. J Biol Chem. 1978;253(19):6630-6632.
[2]. Ignatochkina AV, et al. The messenger RNA decapping and recapping pathway in Trypanosoma. Proc Natl Acad Sci U S A. 2015;112(22):6967-6972.