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(S)-Higenamine hydrobromide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(S)-Higenamine hydrobromide图片
CAS NO:105990-27-0
包装:1mg
市场价:3780元

产品介绍
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide，Higenamine 的 S 型异构体，是苄基异喹啉生物碱生物合成的起始化合物，由去甲月桂碱合酶 (NCS) 将多巴胺和 4-羟基苯乙醛 (4-HPAA) 缩合生成。
Cas No.105990-27-0
别名(S)-(-)-去甲乌药碱氢溴酸盐,(S)-Norcoclaurine hydrobromide
分子式C16H18BrNO3
分子量352.22
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].

[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.