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Melicopine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Melicopine图片
CAS NO:568-01-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
An acridone alkaloid with antimalarial and anticancer activities
Cas No.568-01-4
Canonical SMILESO=C1C2=C(N(C)C3=C4OCOC4=C(C(OC)=C13)OC)C=CC=C2
分子式C17H15NO5
分子量313.3
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Melicopine is an acridone alkaloid that has been found inZ. simulansand has antimalarial and anticancer activities.1It is active against the chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains ofP. falciparumwith IC50values of 29.7 and 33.7 µg/ml, respectively. Melicopine is cytotoxic to PC-3M and LNCaP prostate cancer, but not non-cancerous HEK293, cells (IC50s = 47.9, 37.8, and >100 µg/ml, respectively).

1.Wang, C., Wan, J., Mei, Z., et al.Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans HancePharmacogn. Mag.10(37)73-76(2014)