CAS NO: | 60676-56-4 |
包装 | 价格(元) |
250µg | 电议 |
1mg | 电议 |
Cas No. | 60676-56-4 |
Canonical SMILES | ON1[C@@]2([H])[C@]3(C[C@](N4C(C5=CC=CC=C5N=C4[C@H](C(C)C)OC(C)=O)=O)([H])C(O3)=O)C6=CC=CC=C6N2C([C@@H]1C)=O |
分子式 | C28H28N4O7 |
分子量 | 532.5 |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 µM.1Tryptoquivaline D (1-100 µM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2 1.Prata-Sena, M., Ramos, A.A., Buttachon, S., et al.Cytotoxic activity of secondary metabolites from marine-derived fungus Neosartorya siamensis in human cancer cellsPhytother. Res.30(11)1862-1871(2016) 2.Ramos, A.A., Castro-Carvalho , B., Prata-Sena, M., et al.Can marine-derived fungus Neosartorya siamensis KUFA 0017 extract and its secondary metabolites enhance antitumor activity of doxorubicin• An in vitro survey unveils interactions against lung cancer cellsEnviron. Toxicol.35(4)507-517(2020) |