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(+)-Biotin 4-Amidobenzoic Acid(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+)-Biotin 4-Amidobenzoic Acid(sodium salt)图片
CAS NO:102418-74-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Cas No.102418-74-6
别名生物素4-氨基苯甲酸钠盐
Canonical SMILES[O-]C(C1=CC=C(NC(CCCC[C@@H]2SC[C@@]3([H])[C@]2([H])NC(N3)=O)=O)C=C1)=O.[Na+]
分子式C17H20N3O4S•Na
分子量385.4
溶解度DMSO: 1 mg/mL,PBS (pH 7.2): 2 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-Biotin 4-amidobenzoic acid is a substrate of biotinidase, which cleaves biotin amide to give biotin in vivo. Biotin is an essential coenzyme for certain carboxylases and is used to modify histones and regulate gene transcription. Biotinidase has key roles in intestinal absorption of biotin, the transport of biotin in plasma, and in the regulation of histone biotinylation. (+)-Biotin 4-amidobenzoic acid is hydrolyzed by biotinidase to release 4-aminobenzoic acid (PABA), which can be quantified by either fluorescent or colorimetric methods. This approach is used in biotinidase activity assays in newborn screening protocols to evaluate biotinidase deficiency.