您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > N-Despropyl Ropinirole
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
N-Despropyl Ropinirole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-Despropyl Ropinirole图片
CAS NO:106916-16-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An active metabolite of ropinirole
Cas No.106916-16-9
别名1,3-二氢-4-[2-(丙基氨基)乙基]-2H-吲哚-2-酮
Canonical SMILESO=C1NC2=CC=CC(CCNCCC)=C2C1
分子式C13H18N2O
分子量218.3
溶解度DMF: 25 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-Despropyl ropinirole is an active metabolite of the dopamine D2receptor agonist ropinirole .1It increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4receptors (EC50s = 0.63, 0.063, and 1.23 µM, respectively). N-Despropyl ropinirole is also a potential impurity found in commercial preparations of ropinirole.2

1.Coldwell, M.C., Boyfield, I., Brown, T., et al.Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cellsBr. J. Pharmacol.127(7)1696-1702(1999) 2.Coufal, P., Stulik, K., Claessens, H.A., et al.Separation and quantification of ropinirole and some impurities using capillary liquid chromatographyJ. Chromatogr. B Biomed. Sci. Appl.732(2)437-444(1999)