| CAS NO: | 529-49-7 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| Cas No. | 529-49-7 |
| 别名 | 1,3,7-三羟基-9H-氧杂蒽-9-酮,NSC 329491; 1,3,7-Trihydroxyxanthone |
| Canonical SMILES | O=C1C2=CC(O)=CC=C2OC3=CC(O)=CC(O)=C13 |
| 分子式 | C13H8O5 |
| 分子量 | 244.2 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Gentisein is a xanthone that has been found inH. annulatumand has diverse biological activities.1,2,3It scavenges DPPH radicals and inhibits the activity of α-glucosidase in cell-free assays (IC50s = 23.3 and 14.7 µM, respectively).1,2Gentisein is cytotoxic against K562 chronic multiple leukemia cells, drug-sensitive HL-60 acute promyelocyte leukemia cells, and multidrug-resistant HL-60/DOX cells (IC50s = 102, 90.9, and 88.3 µM, respectively).3 1.Zhong, F.-F., Chen, Y., and Yang, G.-Z.Prenylated xanthones from the bark of Garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activitiesMolecules15(10)7438-7449(2008) 2.Liu, Y., Zou, L., Ma, L., et al.Synthesis and pharmacological activities of xanthone derivatives as α-glucosidase inhibitorsBioorg. Med. Chem.14(16)5683-5690(2006) 3.Biljali, S., Nedialkov, P., Zheleva-Dimitrova, D., et al.Cytotoxic effects and multidrug resistance modulation by five benzophenones and a xanthone Isolated from Hypericum annulatum Moris SUBSP. AnnulatumBiotechnol. Biotechnol. Equip.27(1)3561-3568(2014) |
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