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N,N&rsquo-Diphenethylurea
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N,N&rsquo-Diphenethylurea图片
CAS NO:5467-84-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
A bacterial metabolite with diverse biological activities
Cas No.5467-84-5
Canonical SMILESO=C(NCCC1=CC=CC=C1)NCCC2=CC=CC=C2
分子式C17H20N2O
分子量268.4
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml,Ethanol: 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N,N’-Diphenethylurea is a bacterial metabolite that has been found inStreptomycesand has diverse biological activities.1It inhibitsStreptomyceschitin synthase 1 (IC50= 14 µg/ml) but notC. albicanschitin synthase 2 when used at concentrations up to 280 µg/ml. N,N’-Diphenethylurea is active against the fungusC. neoformansand the plant pathogenic fungusR. solani(MIC = 50 µg/ml for both).2It enhances insulin-induced adipocyte differentiation in 3T3-L1 and C3H/10T1/2 cells when used at concentrations of 30 and 100 µM.3

1.Iwai, Y., Hirano, A., Awaya, J., et al.1,3-Diphenethylurea from Streptomyces sp. No. AM-2498J. Antibiot. (Tokyo)31(4)375-376(1978) 2.Kim, N.R., Hwang, E.I., Bong, S.K., et al.Isolation of Candida albicans chitin synthase 1 inhibitor from Steptomyces sp. A6705 and its characterizationJ. Microbiol. Biotechnol.15(4)895-898(2005) 3.Choi, S.-S., Cha, B.-Y., Kagami, I., et al.N,N’-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cellsJ. Antibiot. (Tokyo)64(3)277-280(2011)