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FAK inhibitor 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FAK inhibitor 2图片
CAS NO:2354405-14-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
FAK inhibitor 2 是一种有效的粘着斑激酶 (FAK) 抑制剂,IC50 值为 0.07?nM,有抗肿瘤和抗血管生成活性。
Cas No.2354405-14-2
Canonical SMILESO=C(NC)C(C=CC=C1)=C1NC2=C(C(F)(F)F)C=NC(NC3=CC=C(C(N4CCN(C(SCCN(C)C)=S)CC4)=O)C=C3)=N2
分子式C29H33F3N8O2S2
分子量646.75
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 ?of 0.07?nM, with antitumor and anti-angiogenesis activities[1]. IC50: 0.07?nM (FAK)[1]

[1]. Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.