| CAS NO: | 22199-08-2 |
| 包装: | 250mg |
| 市场价: | 450元 |
| Cas No. | 22199-08-2 |
| 别名 | 磺胺嘧啶银,AgSD |
| Canonical SMILES | NC(C=C1)=CC=C1S2(=O[Ag+][N]3=CC=C[N-]C3=N2)=O |
| 分子式 | C10H9AgN4O2S |
| 分子量 | 357.14 |
| 储存条件 | 4℃, stored under nitroge |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1]. Silver sulfadiazine (AgSD) is a topical antibiotic used to the research of bacterial infection in burns[2]. [1]. Strydom SJ, et al. Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity. Nanomedicine. 2013;9(1):85-93. [2]. Munhoz DR, et al. Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing. Int J Biol Macromol. 2019;141:504-510. |
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