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(S)-Seco-Duocarmycin SA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S)-Seco-Duocarmycin SA图片
CAS NO:152785-82-5
包装:5mg
市场价:14850元

产品介绍
(S)-Seco-DuocarmycinSA是一种DNA烷化剂(DNAalkylator),可作为抗体药物偶联物的毒素部分(ADCcytotoxin)起作用。
Cas No.152785-82-5
Canonical SMILESClC[C@H]1C2=C(C=C(O)C3=C2C=C(C(OC)=O)N3)N(C(C4=CC5=CC(OC)=C(OC)C(OC)=C5N4)=O)C1
分子式C25H24ClN3O7
分子量513.93
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].

[1]. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.