CAS NO: | 179030-22-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 179030-22-9 |
别名 | N-乙酰-葡糖胺基噻唑啉 |
Canonical SMILES | O[C@@H]1[C@]2([H])[C@](SC(C)=N2)([H])O[C@@H]([C@H]1O)CO |
分子式 | C8H13NO4S |
分子量 | 219.3 |
溶解度 | DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA; Ki= 180 nM).1It is active againstV. campbellii(MIC = 0.5 µM).2 1.Macauley, M.S., and Vocadlo, D.J.Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcaseBiochim. Biophys. Acta1800(2)107-121(2010) 2.Meekrathok, P., Stubbs, K.A., Aunkham, A., et al.NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 β-N-AcetylglucosaminidaseFEBS J.287(22)4982-4995(2020) |