CAS NO: | 1173021-92-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Cas No. | 1173021-92-5 |
别名 | 恩诺沙星-D5,BAY Vp 2674-d5; PD160788-d5 |
Canonical SMILES | O=C1C2=CC(F)=C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])[2H])C=C2N(C4CC4)C=C1C(O)=O |
分子式 | C19H17D5FN3O3 |
分子量 | 364.4 |
溶解度 | DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 1 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Enrofloxacin-d5is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic.1It is active against panels ofCampylobacter,E. coli, andSalmonellaisolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates ofL. intracellularis(MICs = 0.125-0.5 µg/ml).2Enrofloxacin inhibits bacterial DNA gyrase.3In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenicE. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections. 1.Randall, L., Ridley, A., Lemma, F., et al.In vitro investigations into the use of antimicrobials in combination to maintain efficacy of fluoroquinolones in poultryRes. Vet. Sci.10847-53(2016) 2.Pereira, C.E.R., Resende, T.P., Vasquez, E., et al.In vitro antimicrobial activity against equine Lawsonia intracellularis strainsEquine Vet. J.51(5)665-668(2019) 3.Slate, A.R., Bandyopadhyay, S., Francis, K.P., et al.Efficacy of enrofloxacin in a mouse model of sepsisJ. Am. Assoc. Lab. Anim. Sci.53(4)381-386(2014) |