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Tuberculosis inhibitor 3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Tuberculosis inhibitor 3图片
CAS NO:2219325-28-5
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Tuberculosis inhibitor 3 (compound 2i) 对敏感性，和耐性的MTB 菌株均具有良好的抗结核活性。Tuberculosis inhibitor 3 (compound 2i) 显示出良好的药代活性和口服生物利用度。
Cas No.2219325-28-5
分子式C21H22F6N4O3S
分子量524.48
溶解度DMSO : 27.5 mg/mL (52.43 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC< 0.016 µg/mL) against drug-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability[1].

Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) shows acceptable PK properties with the AUC of 2489 h•ng/mL) is. The Tmax of Tuberculosis inhibitor 3 is 0.25 h[1].

[1]. Kai Lv, et al. Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety. Eur J Med Chem. 2018 May 10;151:1-8.