CAS NO: | 1135688-47-9 |
包装 | 价格(元) |
500μg | 电议 |
1mg | 电议 |
5mg | 电议 |
Cas No. | 1135688-47-9 |
别名 | Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone |
化学名 | methyl-14S-(2-fluoroacetyl)-11S-isopropyl-8S-(3-methoxy-3-oxopropyl)-5S-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate |
Canonical SMILES | C[C@H](NC(OCC1=CC=CC=C1)=O)C(N[C@@H](CCC(OC)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(OC)=O)C(CF)=O)=O)=O)=O |
分子式 | C28H39FN4O10 |
分子量 | 610.6 |
溶解度 | 10mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2] Reference: |