Bendiocarb is a broad-spectrum carbamate insecticide and an inhibitor of acetylcholinesterase (K_i= 111 nM for the human enzyme).¹It is active against several species, including second stage nymph German cockroaches (B. germanica; IC₅₀=<0.5 mg/ft²) and adult yellow fever mosquitoes (A. aegypti; IC₅₀=<0.03 mg/ft²).²It is toxic to mammalian species with an oral LD₅₀value of 45 mg/kg for male rats and female mice, but it is metabolized and excreted rapidly and has a dermal LD₅₀of 800 mg/kg after a 24-hour exposure. Formulations containing bendiocarb have been used in the indoor control of insects, including for mosquitoes in areas with malaria transmission.

1.Verma, A., Wong, D.M., Islam, R., et al.3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiaeBioorg. Med. Chem.23(6)1321-1340(2015) 2.Brooker, P.J., Gates, P.S., Gillon, J., et al.Insecticidal activity of certain benzodioxolyl carbamatesPestic. Sci.3(6)735-744(1972)