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Bendiocarb
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bendiocarb图片
CAS NO:22781-23-3
包装:100mg
市场价:378元

产品介绍
A broad-spectrum carbamate insecticide
Cas No.22781-23-3
别名恶虫威
Canonical SMILESCC1(C)OC2=C(OC(NC)=O)C=CC=C2O1
分子式C11H13NO4
分子量223.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml,Ethanol: 5 mg/ml
储存条件Store at Room temperature
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bendiocarb is a broad-spectrum carbamate insecticide and an inhibitor of acetylcholinesterase (Ki= 111 nM for the human enzyme).1It is active against several species, including second stage nymph German cockroaches (B. germanica; IC50=<0.5 mg/ft2) and adult yellow fever mosquitoes (A. aegypti; IC50=<0.03 mg/ft2).2It is toxic to mammalian species with an oral LD50value of 45 mg/kg for male rats and female mice, but it is metabolized and excreted rapidly and has a dermal LD50of 800 mg/kg after a 24-hour exposure. Formulations containing bendiocarb have been used in the indoor control of insects, including for mosquitoes in areas with malaria transmission.

1.Verma, A., Wong, D.M., Islam, R., et al.3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiaeBioorg. Med. Chem.23(6)1321-1340(2015) 2.Brooker, P.J., Gates, P.S., Gillon, J., et al.Insecticidal activity of certain benzodioxolyl carbamatesPestic. Sci.3(6)735-744(1972)