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LMD-009
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LMD-009图片
CAS NO:950195-51-4
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
LMD-009是选择性CCR8非肽激动剂。LMD-009以高效力介导趋化性,肌醇磷酸盐积累和钙释放,EC50为11至87nM。
Cas No.950195-51-4
Canonical SMILESO=C1NCN(CCC2=CC=CC=C2)C13CCN(CC4=CC=CC(OC5=CC=CC=C5OC)=C4)CC3
分子式C29H33N3O3
分子量471.59
溶解度DMSO: 250 mg/mL (530.12 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1].

[1]. Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72(2):327-40.