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Hibifolin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hibifolin图片
CAS NO:55366-56-8
包装:5mg
市场价:1350元

产品介绍
Hibifolin是一种黄酮醇糖苷,是潜在的腺苷脱氨酶(ADA)抑制剂。Hibifolin可以保护神经元免受beta-淀粉样蛋白诱导的神经毒性。
Cas No.55366-56-8
别名棉花皮素-8-O-葡萄糖醛酸苷
Canonical SMILESO[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C3C(C(C(O)=C(C4=CC=C(O)C(O)=C4)O3)=O)=C(O)C=C2O
分子式C21H18O14
分子量494.36
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Hibifolin, a flavonol glycoside, is a potential inhibitor of adenosine deaminase (ADA), with a Ki of 49.92 μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity[1][2].

[1]. K G Arun, et al. Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study. Comput Biol Chem. 2016 Oct;64:353-358. [2]. Judy T T Zhu, et al. Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2009 Sep 18;461(2):172-6.