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C18:1 Ceramide(d18:1/18:1(9Z))
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
C18:1 Ceramide(d18:1/18:1(9Z))图片
CAS NO:5966-28-9
包装:5mg
市场价:1194元

产品介绍
Cas No.5966-28-9
别名N-油酰基-D-鞘氨醇,Cer(d18:1/18:1(9Z))
化学名N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-9Z-octadecenamide
Canonical SMILESOC[C@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC
分子式C36H69NO3
分子量563.9
溶解度Chloroform: Soluble,DMF: 0.15 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

C18:1 Ceramide is a naturally occurring ceramide.[1][2][3] Levels of C18:1 ceramide are elevated in overweight and insulin-resistant mice and cattle.[1][2] C18:1 Ceramide is also increased in the plasma and ovarian tissue of patients with advanced ovarian cancer. [3]

Reference:
[1]. Sajan, M.P., Ivey, R.A., Lee, M.C., et al. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation. J. Lipid Res. 56(1), 70-80 (2015).
[2]. Rico, J.E., Bandaru, V.V., Dorskind, J.M., et al. Plasma ceramides are elevated in overweight Holstein dairy cows experiencing greater lipolysis and insulin resistance during the transition from late pregnancy to early lactation. J. Dairy Sci. 98(11), 7757-7770 (2015).
[3]. Knapp, P., Bodnar, L., Blachnio-Zabielska, A., et al. Plasma and ovarian tissue sphingolipids profiling in patients with advanced ovarian cancer. Gynecol. Oncol. 147(1), 139-144 (2017).