Cas No. | 65996-58-9 |
别名 | 2-氨基-3,5-二氢吡咯并[3,2-D]嘧啶-4-酮 |
Canonical SMILES | NC(N1)=NC2=C(NC=C2)C1=O |
分子式 | C6H6N4O |
分子量 | 150.1 |
溶解度 | DMF: 2.5 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: slightly soluble,PBS (pH 7.2): slightly soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection. |