CAS NO: | 144860-69-5 |
包装 | 价格(元) |
250μg | 电议 |
1mg | 电议 |
Cas No. | 144860-69-5 |
别名 | 雷弗霉素C |
化学名 | butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-(3-methylbutyl)-1,7-dioxaspiro[5.5]undec-3-yl] ester |
Canonical SMILES | CC(/C=C/[C@@H]1O[C@@](CC[C@@H]2C)(CC[C@]1(OC(CCC(O)=O)=O)CCC(C)C)O[C@@H]2C/C=C(/C=C/[C@@H]([C@H](/C=C/C(O)=O)C)O)C)=C\C(O)=O |
分子式 | C37H54O11 |
分子量 | 674.8 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs = 2.0 and >500 ug/ml at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50 = 1.58 ug/ml) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50 = 2.0 ug/ml for both). |