| Cas No. | 77879-90-4 |
| 别名 | 褐黄癌菌素V |
| 化学名 | 4-(6-deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one |
| Canonical SMILES | O=C(O1)C2=C(C(OC)=CC(C=C)=C2)C3=C1C4=C([C@H]5O[C@@]([H])([C@H](O)C)[C@H](O)[C@H]5O)C=CC(O)=C4C(OC)=C3 |
| 分子式 | C27H26O9 |
| 分子量 | 494.5 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Gilvocarcin V is an antitumor antibiotic with a coumarin-based aromatic structure that was orignally isolated from the culture broth of S. gilvotanareus. It is strongly active against Gram-positive bacteria such as S. aureus and B. subtilis and efficacious against experimental tumors including sarcoma 180, Ehrlich carcinoma, Meth I fibrosarcoma, MH134 hepatoma, and lymphocytic leukemia P388. Gilvocarcin V inhibits DNA synthesis by promoting the selective cross-linking of both histone H3 and the heat shock protein, GRP78 to DNA when photoactivated by near-UV or visible light. |
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