Cas No. | 38432-87-0 |
化学名 | 9α,11β,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
Canonical SMILES | O[C@@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C1 |
分子式 | C20H34O5 |
分子量 | 354.5 |
溶解度 | DMF: 100 mg/ml,DMSO: 100 mg/ml,Ethanol: 100 mg/ml,PBS pH 7.2: 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo. Normal human urinary excretion of 11β-PGF2α is about 54 ng/mmol creatinine, which is increased nearly 3-fold upon allergen-induced bronchoconstriction in asthmatics. It is equipotent to PGF2α in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation. 11β-PGF2α inhibits ADP or thrombin-induced human platelet aggregation at concentrations of 0.14 to 2.8 uM. |