Cas No. | 13100-69-1 |
化学名 | 5,6-epoxy-5,6-dihydro-retinoic acid |
Canonical SMILES | CC1(O2)C2(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)C(C)(C)CCC1 |
分子式 | C20H28O3 |
分子量 | 316.4 |
溶解度 | Chloroform: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s = 77, 35, and 4 nM for RARα, RARβ, and RARγ, respectively). 5,6-epoxy RA (1 uM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid , which is a metabolite of vitamin A. |